PDE5-IN-15
Product Specifications
CAS Number
366444-83-9
Target
PDE
Related Pathways
Metabolism
Bioactivity
PDE5-IN-15 (compound 21) is a xanthine derivative and PDE5 inhibitor with IC50 values of 0.002 ?M for hPDE5, 0.180 ?M for bPDE6, 2.85 ?M for bPDE1, and 2.22 ?M for hPDE3. It exhibits good oral bioavailability in dogs and is applicable in research related to male erectile dysfunction.
Smiles
O=C1C=2NC(=NC2N(C(=O)N1C)CC(C)C)CC3=CN=CC4=CC=C(OC)C=C43
Molecular Formula
C21H23N5O3
Molecular Weight
393.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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