MRS2690 disodium
Product Specifications
Target
Calcium Channel, P2Y Receptor, p38 MAPK
Related Pathways
Membrane transporter/Ion channel, MAPK, Metabolism, Neuroscience, GPCR/G Protein
Bioactivity
MRS2690 disodium is a selective agonist of the P2Y14 receptor. It inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and causing concentration-dependent vasoconstriction in porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38, and stimulates [35S]GTPγS binding on the membrane of RBL-2H3 cells. It also enhances the β-hexosaminidase (β-Hex) release induced by antigen (NP-BSA) and C3a. This compound is useful for research in ischemic heart disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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