What is the catalog number for SMI-10B13?

The catalog number for SMI-10B13 is T212456.

What sizes are available for SMI-10B13?

SMI-10B13 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does SMI-10B13 come in?

SMI-10B13 is available in 2 different pack sizes.

Is SMI-10B13 in stock?

SMI-10B13 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SMI-10B13?

SMI-10B13 is manufactured by Molfinity.

What is the estimated delivery time for SMI-10B13?

Estimated delivery time for SMI-10B13 is approximately 10 business day(s), depending on your location.

SMI-10B13

Product Specifications

CAS Number

2502294-68-8

Target

Interleukin, STAT

Related Pathways

Immunology/Inflammation, Stem Cells, JAK/STAT signaling

Bioactivity

SMI-10B13 is an inhibitor of oncostatin M (OSM) with a dissociation constant (KD) of 6.6 μM. It effectively inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines, with IC50 values of 136 nM and 164 nM, respectively. SMI-10B13 demonstrates antitumor activity in a human breast cancer mouse model.