Antifolate agent 1
Product Specifications
CAS Number
518063-75-7
Target
Antifolate
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
Antifolateagent 1 (Compound 1) is an antifolate agent featuring a single-carbon bridge. It lacks RFC transport, shows no affinity for FRα and FRβ, and exhibits no GARFTase inhibition activity. Antifolateagent 1 serves as a negative control in the development of folate receptor-targeted antifolate agents.
Smiles
O=C1C2=C(NC(CC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=C2)NC(N)=N1
Molecular Formula
C19H19N5O6
Molecular Weight
413.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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