DBCO-HS-PEG2-VA-PABC-SG3199
Product Specifications
CAS Number
3052634-58-6
Target
DNA Alkylator/Crosslinker, Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
DBCO-HS-PEG2-VA-PABC-SG3199 is a drug-linker conjugate for ADC (antibody-drug conjugate) that features a SG3199-based DNA minor groove cross-linking agent and a cleavable linker. This compound is suitable for the synthesis of ADCs.
Smiles
C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(COCCOCCNS(NC(CCCC(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3)=O)(=O)=O)=O)C(C)C)=O)C)=O)C=C1)(=O)N5C=6C(C(=O)N7[C@]([C@@H]5O)(CC(C)=C7)[H])=CC(OC)=C(OCCCCCOC8=C(OC)C=C9C(=C8)N=C[C@]%10(N(C9=O)C=C(C)C%10)[H])C6
Molecular Formula
C75H86N10O18S
Molecular Weight
1447.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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