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JP-2-196 hydrochloride

Product Specifications

Target

E1/E2/E3 Enzyme, Molecular Glues

Related Pathways

PROTAC, Ubiquitination

Bioactivity

JP-2-196 hydrochloride is a covalent molecular glue degrader that specifically targets RNF126. It facilitates the formation of a ternary complex between RNF126 and target proteins (e.g., BRD4, AR-V7), promoting their ubiquitination and proteasomal degradation. JP-2-196 hydrochloride is being explored for potential applications in cancer research, such as prostate cancer and leukemia.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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