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SCL-1

Product Specifications

CAS Number

1061105-16-5

Target

PD-1/PD-L1

Related Pathways

Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis

Bioactivity

SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor that disrupts the interaction between PD-1 and PD-L1. It enhances the numbers of T cells, B cells, and natural killer cells. SCL-1 exhibits potent tumor growth inhibitory effects by inducing effector T cells within the tumor and upregulating the expression of long non-coding RNAs as neoantigens, thereby activating cytotoxic T lymphocytes. SCL-1 is applicable in cancer research, including studies on triple-negative breast cancer.

Smiles

O=C(N1CCCCC1C)C2CCN(C3=NN4C(=NN=C4C(F)(F)F)C=C3)CC2

Molecular Formula

C18H23F3N6O

Molecular Weight

396.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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