VVD-442
Product Specifications
CAS Number
3055318-88-9
Target
Ras, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, MAPK
Bioactivity
VVD-442 is a covalent RAS-PI3K inhibitor that binds covalently to cysteine at position 242 in the RAS-binding domain of PI3Kp110α, thereby inhibiting the interaction between RAS and PI3K. VVD-442 is applicable for research in cancers such as breast cancer.
Smiles
S(=O)(=O)(C1=C(C=C(Br)C=C1)C2=C(Cl)C=CC=C2)N3CCC(C(N[C@@H](/C=C\S(C)(=O)=O)C)=O)(F)CC3
Molecular Formula
C23H25BrClFN2O5S2
Molecular Weight
607.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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