What is the catalog number for PNR-3-80?

The catalog number for PNR-3-80 is T212403.

What sizes are available for PNR-3-80?

PNR-3-80 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PNR-3-80 come in?

PNR-3-80 is available in 2 different pack sizes.

Is PNR-3-80 in stock?

PNR-3-80 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PNR-3-80?

PNR-3-80 is manufactured by Molfinity.

What is the estimated delivery time for PNR-3-80?

Estimated delivery time for PNR-3-80 is approximately 10 business day(s), depending on your location.

PNR-3-80

Product Specifications

CAS Number

1424353-63-8

Target

Endonuclease

Related Pathways

Cell Cycle/Checkpoint

Bioactivity

PNR-3-80 is a selective inhibitor of apoptotic endonuclease G (EndoG), with an IC50 of 0.67 μM, showing greater inhibition than against DNase I. It exhibits no inhibitory activity against DNase II, RNase A, proteases, lactate dehydrogenase, and superoxide dismutase 1. PNR-3-80 effectively protects human prostate cancer cells from cell death induced by Cisplatin and Docetaxel and inhibits DNA damage and autophagy (autophagy) prompted by Etoposide. This compound is applicable in studies of cellular damage.