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NOTA-IMB-RGD

Product Specifications

Target

PD-1/PD-L1, Integrin

Related Pathways

Immunology/Inflammation, Cytoskeletal Signaling, Apoptosis, Cell Cycle/Checkpoint

Bioactivity

NOTA-IMB-RGD is a dual-molecule probe that targets integrin αvβ3 (integrinαvβ3) and programmed death-ligand 1 (PD-L1) . It can block the PD-1/PD-L1 signaling pathway and the tumor vasculature with overexpressed integrin αvβ3. This compound holds potential for research in solid tumors co-expressing PD-L1 and αvβ3, such as gliomas and breast cancer.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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