PARP1-IN-43
Product Specifications
CAS Number
3066798-40-8
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
PARP1-IN-43 (Compound 5350) is a PARP1 inhibitor with an IC50 of 5 nM that can cross the blood-brain barrier (BBB) . It is useful for studying homologous recombination (HR) deficient cancers within the central nervous system (CNS) .
Smiles
O=C1NCC2=C1C=CC=C2C3=CC=CC=4C=C(OC43)C(=O)N5CCN(C(=O)C6CN(C(=O)C)CCC6)CC5
Molecular Formula
C29H30N4O5
Molecular Weight
514.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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