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PARP1-IN-43

Product Specifications

CAS Number

3066798-40-8

Target

PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

PARP1-IN-43 (Compound 5350) is a PARP1 inhibitor with an IC50 of 5 nM that can cross the blood-brain barrier (BBB) . It is useful for studying homologous recombination (HR) deficient cancers within the central nervous system (CNS) .

Smiles

O=C1NCC2=C1C=CC=C2C3=CC=CC=4C=C(OC43)C(=O)N5CCN(C(=O)C6CN(C(=O)C)CCC6)CC5

Molecular Formula

C29H30N4O5

Molecular Weight

514.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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