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DNMT2-IN-2

Product Specifications

Target

DNA Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

DNMT2-IN-2 is a selective inhibitor of DNA methyltransferase 2 (DNMT2) with a KD value of 3.04 μM. It targets a concealed allosteric binding site of DNMT2 and reduces m5C levels in tRNA of MOLM-13 cells. This compound works synergistically with Doxorubicin to impair cell viability and is applicable in cancer research, including studies of cervical cancer and leukemia.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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