URAT1-IN-14
Product Specifications
CAS Number
2516232-89-4
Target
OAT
Related Pathways
Membrane transporter/Ion channel
Bioactivity
URAT1-IN-14 is a potent and orally active inhibitor of uric acid transporter 1 (URAT1) . It demonstrates an IC50 value of 0.72 μM for inhibiting human URAT1 in HEK293 cells and exhibits low cytotoxicity in Hep-G2 cells. URAT1-IN-14 reduces uric acid levels in a hyperuricemia mouse model and is applicable in research on hyperuricemia and gout.
Smiles
O=C(O)C1(SC=2C=CC=CC2N3C=4C=CC=CC4OCC3)CCC1
Molecular Formula
C19H19NO3S
Molecular Weight
341.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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