Basivarsen linker

Basivarsen linker is a connector employed in Zeleciment basivarsen, facilitating the attachment of a Fab antibody (Zeleciment) that targets the TfR1 receptor to an antisense oligonucleotide. Zeleciment basivarsen is studied for its potential application in the treatment of myotonic dystrophy type 1 (DM1) .

C(OC(NCCOCCOCCOCCOCCC(N)=O)=O)[C@H]1[C@@]2([C@]1(CCC3=C(CC2)N(CCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC4=CC=C(COC(N)=O)C=C4)=O)CCCNC(N)=O)=O)C(C)C)=O)N=N3)[H])[H]