IKP-104
Product Specifications
CAS Number
114231-14-0
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
IKP-104 is a microtubule/tubulin inhibitor (IC50 = 1.31 μM) that halts cells in mitosis and the M phase by inhibiting microtubule assembly and inducing cytoskeleton microtubule depolymerization. It suppresses the growth of both murine and human tumor cell lines, exhibiting antitumor effects in mouse ascites tumor and lung cancer models. IKP-104 is applicable in research on cancers such as leukemia, lung cancer, and melanoma.
Smiles
O=C1C=C(C=2C=CC=CC2)N(C=3C=C(OC)C=C(OC)C3Cl)C(C=4C=CC(F)=CC4)=C1C
Molecular Formula
C26H21ClFNO3
Molecular Weight
449.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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