What is the catalog number for EGFR WT/T790M-IN-3?

The catalog number for EGFR WT/T790M-IN-3 is T212301.

What sizes are available for EGFR WT/T790M-IN-3?

EGFR WT/T790M-IN-3 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR WT/T790M-IN-3 come in?

EGFR WT/T790M-IN-3 is available in 2 different pack sizes.

Is EGFR WT/T790M-IN-3 in stock?

EGFR WT/T790M-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR WT/T790M-IN-3?

EGFR WT/T790M-IN-3 is manufactured by Molfinity.

What is the estimated delivery time for EGFR WT/T790M-IN-3?

Estimated delivery time for EGFR WT/T790M-IN-3 is approximately 10 business day(s), depending on your location.

EGFR WT/T790M-IN-3

Product Specifications

Target

Microtubule Associated, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, JAK/STAT signaling

Bioactivity

EGFRWT/T790M-IN-3 is an irreversible, covalent inhibitor of EGFRWT and EGFRT790M with IC50 values of 28.1 nM and 24.6 nM, respectively. It also inhibits tubulin polymerization, exhibiting an IC50 of 5.1 μM. EGFRWT/T790M-IN-3 demonstrates significant antiproliferative effects on HCT116 and T47D cells, with IC50 values of 3.12 μM and 4.12 μM, respectively. This compound is applicable in research pertaining to cancers such as non-small cell lung cancer, colon cancer, and breast cancer.