What is the catalog number for PROTAC c-Met degrader-6?

The catalog number for PROTAC c-Met degrader-6 is T212285.

What sizes are available for PROTAC c-Met degrader-6?

PROTAC c-Met degrader-6 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PROTAC c-Met degrader-6 come in?

PROTAC c-Met degrader-6 is available in 2 different pack sizes.

Is PROTAC c-Met degrader-6 in stock?

PROTAC c-Met degrader-6 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PROTAC c-Met degrader-6?

PROTAC c-Met degrader-6 is manufactured by Molfinity.

What is the estimated delivery time for PROTAC c-Met degrader-6?

Estimated delivery time for PROTAC c-Met degrader-6 is approximately 10 business day(s), depending on your location.

PROTAC c-Met degrader-6

Product Specifications

Target

PROTACs, Apoptosis, c-Met/HGFR

Related Pathways

Apoptosis, PROTAC, Tyrosine Kinase/Adaptors

Bioactivity

PROTACc-Met degrader-6 is a potent and orally active c-Met PROTAC degrader. It effectively promotes the degradation of c-Met protein, with DC50 values of 0.52 nM in EBC-1 cells and 0.45 nM in Hs746T cells. This compound almost completely abolishes the migration and invasion capabilities of tumor cells, significantly induces apoptosis (apoptosis), and arrests the cell cycle at the G0/G1 phase. PROTACc-Met degrader-6 is useful for studying various cancers, including non-small cell lung cancer and gastric cancer.