Anti-inflammatory agent 104
Product Specifications
CAS Number
382630-23-1
Target
TNF
Related Pathways
Apoptosis
Bioactivity
Anti-inflammatory agent 104 (Compound 26) is an anti-inflammatory compound. It inhibits TNF-? synthesis and release in the U937 human macrophage cell line with an IC50 of 0.024 nM. Additionally, Anti-inflammatory agent 104 reduces eosinophil levels in rat lungs by 63%.
Smiles
O(C(=O)C1=C(C)C=CS1)[C@@]2(C(OC)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](Cl)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]
Molecular Formula
C28H32ClFO6S
Molecular Weight
551.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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