What is the catalog number for MS44?

The catalog number for MS44 is T212241.

What sizes are available for MS44?

MS44 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does MS44 come in?

MS44 is available in 2 different pack sizes.

MS44 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MS44?

MS44 is manufactured by Molfinity.

What is the estimated delivery time for MS44?

Estimated delivery time for MS44 is approximately 10 business day(s), depending on your location.

MS44

Product Specifications

Target

PROTACs, Aurora Kinase

Related Pathways

Chromatin/Epigenetic, PROTAC, Cell Cycle/Checkpoint

Bioactivity

MS44 is a potent degrader of aurora kinase B (AURKBPROTAC) with a degradation concentration (DC50) of 103 nM. It effectively and selectively degrades AURKB in a time- and ubiquitin-proteasome system (UPS) -dependent manner, showing specificity for AURKB over AURKA and AURKC. MS44 inhibits the proliferation of various cancer cell lines and strongly induces G2/M arrest. It is useful for studying AURKB-dependent tumors.