NLRP3-IN-82
Product Specifications
CAS Number
3091347-92-8
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-82 (Compound 2b) is an NLRP3 inhibitor that significantly suppresses IL-1β release in HMDM cells with an IC50 of less than 5 nM. This compound is applicable for research into neurological disorders such as Alzheimer's disease, inflammatory conditions like inflammatory bowel disease, and metabolic disorders such as obesity.
Smiles
CN1C[C@]2(N(C=3C=4N(C(=NN3)C5=C(O)C=C(Cl)C(C)=C5)C=CN4)CC[C@]2(CC1)[H])[H]
Molecular Formula
C20H23ClN6O
Molecular Weight
398.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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