Rac1-IN-5
Product Specifications
CAS Number
694515-65-6
Target
Ras, Akt, Acyltransferase
Related Pathways
Metabolism, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, MAPK
Bioactivity
Rac1-IN-5 is a selective, reversible inhibitor of the RAC1 protein with a dissociation constant (KD) of 30 nM. It competes specifically with guanine nucleotides for binding to RAC proteins, effectively blocking RAC1 activity and RAC1-dependent cellular functions. In vivo, Rac1-IN-5 exhibits anti-tumor metastasis effects and can improve survival rates. This compound is applicable for research on aggressive cancers such as triple-negative breast cancer and colon cancer.
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=CC(OC)=CC=C2OC)CCSC3=CC=C(C=C3)C
Molecular Formula
C24H26N2O5S2
Molecular Weight
486.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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