PROTAC BET Degrader-13
Product Specifications
Target
Epigenetic Reader Domain, PROTACs
Related Pathways
Chromatin/Epigenetic, PROTAC
Bioactivity
PROTACBET Degrader-13 (Compound 34) is a TRIM21-based PROTAC (TRIMTAC) degrader that targets BET proteins. It effectively degrades the PML-eGFP-BRD4 fusion protein, causing a near-complete loss of EGFP+ nuclear foci with an EC50 of 1.4 μM.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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