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Nurr1 Agonist 14

Product Specifications

Target

Others, Survivin, NR4A, Calcium Channel, IAP

Related Pathways

Endocrinology/Hormones, Apoptosis, Membrane transporter/Ion channel, Others, Metabolism

Bioactivity

Nurr1 Agonist 14 (Compound 32) is a Nurr1 agonist with an EC50 of 0.09 μM for Nurr1. It exhibits significant neuroprotective activity without being hindered by residual DHODH inhibition. This compound can upregulate neuroprotective genes in dopaminergic neurons, such as SOD2, SESN3, BIRC5, XIAP, FLRT2, and CRMP4. Nurr1 Agonist 14 is useful for studying neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) .

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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