Nurr1 Agonist 14
Product Specifications
Target
Others|||Survivin|||NR4A|||Calcium Channel|||IAP
Related Pathways
Endocrinology/Hormones|||Apoptosis|||Membrane transporter/Ion channel|||Others|||Metabolism
Bioactivity
Nurr1 Agonist 14 (Compound 32) is a Nurr1 agonist with an EC50 of 0.09 ?M for Nurr1. It exhibits significant neuroprotective activity without being hindered by residual DHODH inhibition. This compound can upregulate neuroprotective genes in dopaminergic neurons, such as SOD2, SESN3, BIRC5, XIAP, FLRT2, and CRMP4. Nurr1 Agonist 14 is useful for studying neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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