Aurora kinase ligand-1
Product Specifications
CAS Number
1907679-70-2
Target
Ligands for Target Protein for PROTAC, Aurora Kinase
Related Pathways
PROTAC, Chromatin/Epigenetic, Cell Cycle/Checkpoint
Bioactivity
Aurora kinaseligand-1 (Compound I-4) is an AURKB PROTAC ligand designed to target aurora kinase B. It can conjugate with an E3 ligase ligand and a linker to form the AURKB PROTAC degrader MS44, which is applicable in cancer research.
Smiles
O=C(NC=1C=CC=C(F)C1)CC2=NNC(=C2)NC=3N=CN=C4C=C(OCCCNCCO)C=CC43
Molecular Formula
C24H26FN7O3
Molecular Weight
479.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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