2-ACC
Product Specifications
CAS Number
3091880-01-9
Target
Hedgehog/Smoothened
Related Pathways
GPCR/G Protein, Stem Cells
Bioactivity
2-ACC (2-α-Carboxy cholestanol) is a cholestanol derivative that functions as an activator of the mutant Sonic Hedgehog protein D46A, with an EC50 of approximately 5 μM.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC[C@]1(C[C@@H](O)[C@H](C(O)=O)C2)[H])[H])[H]
Molecular Formula
C28H48O3
Molecular Weight
432.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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