5-Methyl cromolyn disodium
Product Specifications
CAS Number
1221154-42-2
Target
Others
Related Pathways
Others
Bioactivity
5-Methyl cromolyn (C5OH) disodium is a cromolyn analog that acts as an S100P inhibitor. It prevents the interaction between S100P and its receptor RAGE, hinders NF-κB activity and cell proliferation, and enhances apoptosis induced by Gemcitabine. In murine models with PDAC, 5-Methyl cromolyn disodium reduces tumor growth and metastasis, thereby extending survival. This compound is suitable for pancreatic cancer research, including studies on pancreatic ductal adenocarcinoma (PDAC) .
Smiles
O=C(C(OC1=CC=CC(OCCC(CCOC(C=CC=C2OC(C([O-])=O)=C3)=C2C3=O)O)=C14)=CC4=O)[O-].[Na+].[Na+]
Molecular Formula
C25H18Na2O11
Molecular Weight
540.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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