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PARG-IN-7

Product Specifications

CAS Number

2632343-19-0

Target

Poly (ADP-ribose) Glycohydrolase (PARG)

Related Pathways

Cell Cycle/Checkpoint

Bioactivity

PARG-IN-7 (Example 38) is a Poly ADP-ribose glycohydrolase (PARG) inhibitor with an IC50 of less than 0.1 ?M. It reduces the viability of HCC1806-XRCC1 knockdown (KD) cells, exhibiting an IC50 of less than 1 ?M. PARG-IN-7 is applicable in cancer research.

Smiles

N#CC1(NS(=O)(=O)C=2C=C3C(C=NN3C4=NN=C(S4)C(F)F)=C(C2)N5CCN(C(=O)C(C)C)CC5)CC1

Molecular Formula

C22H24F2N8O3S2

Molecular Weight

550.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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