FGFR-IN-22
Product Specifications
CAS Number
1431872-18-2
Target
FGFR
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
FGFR-IN-22 (Compound 23) is an FGFR inhibitor with IC50 values of 0.631 nM for FGFR1, 1.26 nM for FGFR2, 0.851 nM for FGFR3, and 1 nM for FGFR4. It effectively inhibits cell proliferation dependent on FGFR1 and FGFR3 signaling pathways. FGFR-IN-22 is applicable in research related to cancers such as chronic lymphocytic leukemia (CLL) .
Smiles
FC=1C(OC)=CC(OC)=CC1N(C2=NC3=NC(=CN=C3C=C2)C=4C=NN(C4)C)CC5=NC=CN5
Molecular Formula
C23H21FN8O2
Molecular Weight
460.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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