What is the catalog number for Nogo-B-IN-1?

The catalog number for Nogo-B-IN-1 is T212139.

What sizes are available for Nogo-B-IN-1?

Nogo-B-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Nogo-B-IN-1 come in?

Nogo-B-IN-1 is available in 2 different pack sizes.

Is Nogo-B-IN-1 in stock?

Nogo-B-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nogo-B-IN-1?

Nogo-B-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for Nogo-B-IN-1?

Estimated delivery time for Nogo-B-IN-1 is approximately 10 business day(s), depending on your location.

Nogo-B-IN-1

Product Specifications

Target

Apoptosis, NF-κB, Bcl-2 Family, Akt, PI3K

Related Pathways

Apoptosis, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, NF-κB

Bioactivity

Nogo-B-IN-1 ((S, R) -4v) is a covalent inhibitor targeting Nogo-B. It suppresses osteosarcoma (OS) progression by inhibiting Nogo-B activity and the PI3K/AKT/NF-κB/Bcl-2 signaling pathways. Nogo-B-IN-1 hinders proliferation of OS 143B cells (IC50= 0.28 μM) and induces apoptosis. This compound is applicable for targeted OS research.