UNC9750
Product Specifications
CAS Number
2967648-29-7
Target
PDGFR|||Others|||DAPK|||DYRK
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis|||Cell Cycle/Checkpoint|||Others
Bioactivity
UNC9750 is an inhibitor of inositol phosphate multikinase (IPMK), with IC50 values of 31.6 nM for IPMK and 374 nM for IP6K2. It effectively suppresses the accumulation of InsP5, a direct product of IPMK kinase activity, without affecting InsP6 or InsP7 levels. Additionally, UNC9750 inhibits over 75% of the activity of four kinases: DAPK1, DYRK1B, PDGFR, and KDR. This compound is applicable in glioblastoma research.
Smiles
N1=NNC(=N1)C=2C=CC3=NOC(C=4C=CC=C(C4)C5CCN(CC5)C6CCC6)=C3C2
Molecular Formula
C23H24N6O
Molecular Weight
400.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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