SMU-C68
Product Specifications
CAS Number
2677039-75-5
Target
NF-κB, p38 MAPK, TLR
Related Pathways
Immunology/Inflammation, MAPK, NF-κB
Bioactivity
SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM) . It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.
Smiles
O=C(OC(C)C)C1=C(SC2=C1CCC2)NC(=S)NC3=CC=CC4=NC=CC=C43
Molecular Formula
C21H21N3O2S2
Molecular Weight
411.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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