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SMU-C68

Product Specifications

CAS Number

2677039-75-5

Target

NF-κB, p38 MAPK, TLR

Related Pathways

Immunology/Inflammation, MAPK, NF-κB

Bioactivity

SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM) . It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.

Smiles

O=C(OC(C)C)C1=C(SC2=C1CCC2)NC(=S)NC3=CC=CC4=NC=CC=C43

Molecular Formula

C21H21N3O2S2

Molecular Weight

411.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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