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BAL-1516

Product Specifications

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

BAL-1516 is a brain-penetrant and highly selective NLRP3 inhibitor (IC50=14.2 nM) . It significantly inhibits the release of interleukin-1β and interleukin-18 in microglial neuroinflammation models (IC50=11-59 nM) . BAL-1516 holds potential for research in neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as systemic inflammatory disorders.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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