BAL-1516
Product Specifications
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
BAL-1516 is a brain-penetrant and highly selective NLRP3 inhibitor (IC50=14.2 nM) . It significantly inhibits the release of interleukin-1? and interleukin-18 in microglial neuroinflammation models (IC50=11-59 nM) . BAL-1516 holds potential for research in neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as systemic inflammatory disorders.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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