(R) -CDK2 degrader 6
Product Specifications
CAS Number
3083777-50-5
Target
Molecular Glues, CDK
Related Pathways
Cell Cycle/Checkpoint, PROTAC
Bioactivity
(R) -CDK2 degrader 6 (Compound 7) is the R enantiomer of CDK2 degrader 6. It functions as a selective molecular glue degrader for CDK2, with a DC50 of 27.0 nM within 24 hours. This compound can be utilized in breast cancer research.
Smiles
C(F)(F)(F)C12CC(C1)(C2)C=3OC(N[C@@H]4[C@@H](C)N(C4)C5=CC(F)=C(C(F)=C5)[C@@H]6C(=O)NC(=O)CC6)=NN3
Molecular Formula
C23H22F5N5O3
Molecular Weight
511.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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