Microtubule stabilizer-1
Product Specifications
CAS Number
2699937-76-1
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
Microtubule stabilizer-1 (compound 69) is a microtubule (MT) stabilizer capable of crossing the blood-brain barrier. It increases the levels of acetylated α-tubulin (AcTub) and prevents the characteristic loss of neuronal microtubules observed after incubation with Okadaic acid. This compound is useful in researching Alzheimer's disease (AD) and related neurodegenerative tauopathies.
Smiles
N([C@@H](C(C)(C)C)C)C1=C(C(Cl)=NC=2N1N=CN2)C3=C(F)C=C(C#N)C=C3F
Molecular Formula
C18H17ClF2N6
Molecular Weight
390.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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