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HPK1-IN-61

Product Specifications

CAS Number

875638-86-1

Target

MAPK, Src, Bcr-Abl

Related Pathways

Cytoskeletal Signaling, MAPK, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

HPK1-IN-61 (Compound 1) serves as an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with a Ki of 0.4 nM, and also inhibits Abl with an IC50 of less than 0.51 nM. Additionally, HPK1-IN-61 displays inhibitory activity against LCK, with an IC50 of 24 nM.

Smiles

O=C(C=1C=C(C=CC1N)C2=CN=C3NC=C(C=4C=CC=CC4OC)C3=C2)N(C)C

Molecular Formula

C23H22N4O2

Molecular Weight

386.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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