What is the catalog number for LCZ960?

The catalog number for LCZ960 is T212056.

What sizes are available for LCZ960?

LCZ960 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does LCZ960 come in?

LCZ960 is available in 2 different pack sizes.

LCZ960 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LCZ960?

LCZ960 is manufactured by Molfinity.

What is the estimated delivery time for LCZ960?

Estimated delivery time for LCZ960 is approximately 10 business day(s), depending on your location.

LCZ960

Product Specifications

CAS Number

1067877-83-1

Target

Glucokinase

Related Pathways

Metabolism

Bioactivity

LCZ960 is an orally active glucokinase (GK) activator that stimulates GK activity in liver cells in vitro and enhances glucose uptake in vivo by activating hepatic GK. It effectively lowers blood glucose levels in diet-induced obesity (DIO) in mice. LCZ960 maintains normal blood sugar and improves glucose tolerance in DIO mice and rats. Additionally, LCZ960 stimulates glycogen synthase flux and increases glycogen turnover in the liver of rats, inducing an increase in hepatic glycogen cycling. This compound is useful for research on obesity and type 2 diabetes induced by high-fat diets.