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MF-DH-300

Product Specifications

CAS Number

2673403-86-4

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. It blocks the interaction between 15-PGDH and PGE2, promoting stem cell proliferation, increasing muscle strength, and enhancing mitochondrial function. Additionally, MF-DH-300 raises the expression of survival motor neuron (SMN) protein and is applicable in research on muscle diseases such as spinal muscular atrophy (SMA) .

Smiles

N#CC1=CC=CC(=C1)N2C=CC=3C=C(C=NC32)C(=O)N4CCCCC4

Molecular Formula

C20H18N4O

Molecular Weight

330.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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