MF-DH-300
Product Specifications
CAS Number
2673403-86-4
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. It blocks the interaction between 15-PGDH and PGE2, promoting stem cell proliferation, increasing muscle strength, and enhancing mitochondrial function. Additionally, MF-DH-300 raises the expression of survival motor neuron (SMN) protein and is applicable in research on muscle diseases such as spinal muscular atrophy (SMA) .
Smiles
N#CC1=CC=CC(=C1)N2C=CC=3C=C(C=NC32)C(=O)N4CCCCC4
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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