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Chloroguanabenz acetate

Product Specifications

CAS Number

2242615-97-8

Target

Adrenergic Receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Bioactivity

Chloroguanabenz (acetate) is an antiprion agent derived from guanabenz, an ?2-adrenergic receptor agonist. It inhibits prion formation in vitro in both yeast and mammalian models. Additionally, Chloroguanabenz (acetate) reduces levels of the truncated huntingtin protein derivative Htt48 in HEK293T cells and is used for studying Huntington's disease.

Smiles

C(C)(O)=O.C(=N/NC(=N)N)\C1=C(Cl)C(Cl)=CC=C1Cl

Molecular Formula

C10H11Cl3N4O2

Molecular Weight

325.58

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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