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XL-3156

Product Specifications

Target

CGAS

Related Pathways

Immunology/Inflammation

Bioactivity

XL-3156 is a potent, selective, and cross-species inhibitor of cGAS. It simultaneously occupies allosteric and orthosteric sites, stabilizing the closed conformation of the activation loop to inhibit the interaction and phase separation of cGAS with DNA. XL-3156 is applicable for research into autoimmune diseases and inflammation.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/390881992801566760/T212003

Available Sizes

Curated Selection

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