MrgprX2-IN-2
Product Specifications
CAS Number
2792205-87-7
Target
MRGPR
Related Pathways
GPCR/G Protein
Bioactivity
MrgprX2-IN-2 (Compound example 12) is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) . It works by inhibiting MRGPRX2-mediated mast cell degranulation and the release of inflammatory mediators, thus blocking non-IgE-dependent immune responses. MrgprX2-IN-2 shows potential for research in the areas of pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.
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N(C=1N2C(=NC(C(F)(F)F)=C2)C=CC1)[C@H]3CC[C@@H](NC(=O)C4=CN(CC(F)(F)F)N=C4Cl)CC3
Molecular Formula
C20H19ClF6N6O
Molecular Weight
508.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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