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ADAR1-IN-1

Product Specifications

CAS Number

2734853-87-1

Target

Apoptosis|||Adenosine Deaminase

Related Pathways

Metabolism|||Apoptosis

Bioactivity

ADAR1-IN-1 is a potent ADAR1 inhibitor. It significantly suppresses the proliferation of DU-145 cells (IC50 = 1.11 ?M), inhibits colony formation, migration, and invasion, and induces cell cycle arrest and apoptosis. ADAR1-IN-1 effectively and safely impedes tumor growth and can be utilized in prostate cancer (PCa) research.

Smiles

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(F)N3)O[C@H](COS(=O)(=O)C4=CC=C(C(F)(F)F)C=C4)[C@H]1O

Molecular Formula

C17H15F4N5O6S

Molecular Weight

493.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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