ADAR1-IN-1
Product Specifications
CAS Number
2734853-87-1
Target
Apoptosis|||Adenosine Deaminase
Related Pathways
Metabolism|||Apoptosis
Bioactivity
ADAR1-IN-1 is a potent ADAR1 inhibitor. It significantly suppresses the proliferation of DU-145 cells (IC50 = 1.11 ?M), inhibits colony formation, migration, and invasion, and induces cell cycle arrest and apoptosis. ADAR1-IN-1 effectively and safely impedes tumor growth and can be utilized in prostate cancer (PCa) research.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(F)N3)O[C@H](COS(=O)(=O)C4=CC=C(C(F)(F)F)C=C4)[C@H]1O
Molecular Formula
C17H15F4N5O6S
Molecular Weight
493.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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