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VNRX-9945

Product Specifications

CAS Number

2396680-45-6

Target

HBV

Related Pathways

Microbiology/Virology

Bioactivity

VNRX-9945 is a potent and orally active HBV capsid assembly modulator (CAM), exhibiting an EC50 value of 2.6 nM. It demonstrates excellent and broad-spectrum antiviral activity against multiple HBV genotypes in vitro, with favorable pharmacokinetic properties across various species. Additionally, VNRX-9945 shows significant antiviral efficacy in the AAV-HBV infected mouse model.

Smiles

C(C(N[C@@H]1CC[C@H](O)CC1)=O)(=O)C2=C(C)C(C(NC3=CC(C)=C(F)C=C3)=O)=C(C)N2C

Molecular Formula

C23H28FN3O4

Molecular Weight

429.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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