VNRX-9945
Product Specifications
CAS Number
2396680-45-6
Target
HBV
Related Pathways
Microbiology/Virology
Bioactivity
VNRX-9945 is a potent and orally active HBV capsid assembly modulator (CAM), exhibiting an EC50 value of 2.6 nM. It demonstrates excellent and broad-spectrum antiviral activity against multiple HBV genotypes in vitro, with favorable pharmacokinetic properties across various species. Additionally, VNRX-9945 shows significant antiviral efficacy in the AAV-HBV infected mouse model.
Smiles
C(C(N[C@@H]1CC[C@H](O)CC1)=O)(=O)C2=C(C)C(C(NC3=CC(C)=C(F)C=C3)=O)=C(C)N2C
Molecular Formula
C23H28FN3O4
Molecular Weight
429.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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