ATF3-IN-1
Product Specifications
CAS Number
2952703-90-9
Target
Ferroptosis, Epigenetic Reader Domain, Glutathione Peroxidase, ROS
Related Pathways
Chromatin/Epigenetic, Apoptosis, Metabolism, Immunology/Inflammation
Bioactivity
ATF3-IN-1 is an inhibitor of both ferroptosis and ATF3. It mitigates oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, offering protection against ischemic stroke. ATF3-IN-1 can reduce ischemia/reperfusion (I/R) injury and enhance neuron survival, demonstrating neuroprotective effects, making it valuable for ischemic stroke research.
Smiles
O=C1C(OC)=C(OC)C(=O)C(=C1C)CCCCCCCCCCOC(=O)N2CCOCC2
Molecular Formula
C24H37NO7
Molecular Weight
451.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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